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| 產(chǎn)品編號(hào) | bs-0345G |
| 英文名稱 | Goat Anti-Human IgM antibody |
| 中文名稱 | 羊抗人IgM |
| 別 名 | Human Immunoglobulin M; hu IgM; 羊抗人-IgM |
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Specific References (2) | bs-0345G has been referenced in 2 publications.
[IF=3.565] Yuan Y et al. CMTM5-v1 inhibits cell proliferation and migration by downregulating oncogenic EGFR signaling in prostate cancer cells. J Cancer
. 2020 Apr 6;11(13):3762-3770. WB ; human.
[IF=1.79] Tang, Jieli, et al. "Studies of Fluorescence Immunosensor Using Eggshell Membrane as Immobilization Matrix." Journal of fluorescence 21.1 (2011): 339-346. Human.
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| 抗體來(lái)源 | Goat |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:1000-5000,IHC-P=1:100-500,IHC-F=1:200-1000,ELISA=1:2000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 性 狀 | Lyophilized |
| 免 疫 原 | Native Human IgM: full length |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein G |
| 緩 沖 液 | 0.01M PBS (pH7.4). |
| 保存條件 | Store at -20℃ stable for 2 years (lyophilized powder). Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences. |
